MYH3‐associated distal arthrogryposis zebrafish model is normalized with para‐aminoblebbistatin

Distal arthrogryposis (DA) is group of syndromes characterized by congenital joint contractures. Treatment development is hindered by the lack of vertebrate models. Here, we describe a zebrafish model in which a common MYH3 missense mutation (R672H) was introduced into the orthologous zebrafish gene...

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Vydáno v:EMBO Mol Med
Hlavní autoři: Whittle, Julia, Antunes, Lilian, Harris, Mya, Upshaw, Zachary, Sepich, Diane S, Johnson, Aaron N, Mokalled, Mayssa, Solnica‐Krezel, Lilianna, Dobbs, Matthew B, Gurnett, Christina A
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2020
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7645368/
https://ncbi.nlm.nih.gov/pubmed/33016623
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/emmm.202012356
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