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Nicotine enhances alcoholic fatty liver in mice: Role of CYP2A5

Tobacco and alcohol are often co-abused. Nicotine can enhance alcoholic fatty liver, and CYP2A6 (CYP2A5 in mice), a major metabolism enzyme for nicotine, can be induced by alcohol. CYP2A5 knockout (cyp2a5(−/−)) mice and their littermates (cyp2a5(+/+)) were used to test whether CYP2A5 has an effect o...

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Vydáno v:Arch Biochem Biophys
Hlavní autoři: Chen, Xue, Owoseni, Emmanuel, salamat, Julia, Cederbaum, Arthur I., Lu, Yongke
Médium: Artigo
Jazyk:Inglês
Vydáno: 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6177319/
https://ncbi.nlm.nih.gov/pubmed/30222954
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.abb.2018.09.012
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