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The K79G Mutation Reshapes the Heme Crevice and Alters Redox Properties of Cytochrome c

The two roles of cytochrome c (cyt c), in oxidative phosphorylation and apoptosis, critically depend on redox properties of its heme iron center. The K79G mutant has served as a parent protein for a series of mutants of yeast iso-1 cyt c. The mutation preserves the Met80 coordination to the heme iro...

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Detalhes bibliográficos
Publicado no:Biochemistry
Main Authors: Deng, Yunling, Zhong, Fangfang, Alden, Stephanie L., Hoke, Kevin R., Pletneva, Ekaterina V.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6177310/
https://ncbi.nlm.nih.gov/pubmed/30142276
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.8b00650
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