Loading...

The K79G Mutation Reshapes the Heme Crevice and Alters Redox Properties of Cytochrome c

The two roles of cytochrome c (cyt c), in oxidative phosphorylation and apoptosis, critically depend on redox properties of its heme iron center. The K79G mutant has served as a parent protein for a series of mutants of yeast iso-1 cyt c. The mutation preserves the Met80 coordination to the heme iro...

Full description

Saved in:
Bibliographic Details
Published in:Biochemistry
Main Authors: Deng, Yunling, Zhong, Fangfang, Alden, Stephanie L., Hoke, Kevin R., Pletneva, Ekaterina V.
Format: Artigo
Language:Inglês
Published: 2018
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6177310/
https://ncbi.nlm.nih.gov/pubmed/30142276
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.8b00650
Tags: Add Tag
No Tags, Be the first to tag this record!