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The K79G Mutation Reshapes the Heme Crevice and Alters Redox Properties of Cytochrome c
The two roles of cytochrome c (cyt c), in oxidative phosphorylation and apoptosis, critically depend on redox properties of its heme iron center. The K79G mutant has served as a parent protein for a series of mutants of yeast iso-1 cyt c. The mutation preserves the Met80 coordination to the heme iro...
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| 出版年: | Biochemistry |
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| 主要な著者: | , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2018
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6177310/ https://ncbi.nlm.nih.gov/pubmed/30142276 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.8b00650 |
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