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Pgc-1α repression and high-fat diet induce age-related macular degeneration-like phenotypes in mice
Age-related macular degeneration (AMD) is the major cause of blindness in the elderly in developed countries and its prevalence is increasing with the aging population. AMD initially affects the retinal pigment epithelium (RPE) and gradually leads to secondary photoreceptor degeneration. Recent stud...
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| Publicado no: | Dis Model Mech |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Company of Biologists Ltd
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6176989/ https://ncbi.nlm.nih.gov/pubmed/29925537 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.032698 |
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