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Pgc-1α repression and high-fat diet induce age-related macular degeneration-like phenotypes in mice

Age-related macular degeneration (AMD) is the major cause of blindness in the elderly in developed countries and its prevalence is increasing with the aging population. AMD initially affects the retinal pigment epithelium (RPE) and gradually leads to secondary photoreceptor degeneration. Recent stud...

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Detaylı Bibliyografya
Yayımlandı:Dis Model Mech
Asıl Yazarlar: Zhang, Meng, Chu, Yi, Mowery, Joseph, Konkel, Brandon, Galli, Susana, Theos, Alexander C., Golestaneh, Nady
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: The Company of Biologists Ltd 2018
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6176989/
https://ncbi.nlm.nih.gov/pubmed/29925537
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.032698
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