Histone Deacetylase Inhibitor (HDACi) Conjugated Polycaprolactone for Combination Cancer Therapy

The short chain fatty acid, 4-phenylbutyric acid (PBA), is used for the treatment of urea cycle disorders and sickle cell disease as an endoplasmic reticulum stress inhibitor. PBA is also known as a histone deacetylase inhibitor (HDACi). We report here the effect of combination therapy on HeLa cance...

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Bibliografiske detaljer
Udgivet i:Biomacromolecules
Main Authors: Kularatne, Ruvanthi N., Washington, Katherine E., Bulumulla, Chandima, Calubaquib, Erika L., Biewer, Michael C., Oupicky, David, Stefan, Mihaela C.
Format: Artigo
Sprog:Inglês
Udgivet: 2018
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6176919/
https://ncbi.nlm.nih.gov/pubmed/29485283
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biomac.8b00221
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