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Histone deacetylase inhibitor (HDACI) mechanisms of action: emerging insights
Initially regarded as “epigenetic modifiers” acting predominantly through chromatin remodeling via histone acetylation, HDACIs, alternatively referred to as lysine deacetylase or simply deacetylase inhibitors, have since been recognized to exert multiple cytotoxic actions in cancer cells, often thro...
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| Hauptverfasser: | , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2014
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4117710/ https://ncbi.nlm.nih.gov/pubmed/24769080 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pharmthera.2014.04.004 |
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