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Screening for genes that regulate the differentiation of human megakaryocytic lineage cells

Different combinations of transcription factors (TFs) function at each stage of hematopoiesis, leading to distinct expression patterns of lineage-specific genes. The identification of such regulators and their functions in hematopoiesis remain largely unresolved. In this study, we utilized screening...

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Bibliographic Details
Published in:Proc Natl Acad Sci U S A
Main Authors: Zhu, Fangfang, Feng, Mingye, Sinha, Rahul, Seita, Jun, Mori, Yasuo, Weissman, Irving L.
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2018
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6176640/
https://ncbi.nlm.nih.gov/pubmed/30150396
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1805434115
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