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GIRK currents in VTA dopamine neurons control the sensitivity of mice to cocaine-induced locomotor sensitization

GABA(B)R-dependent activation of G protein-gated inwardly rectifying potassium channels (GIRK or K(IR)3) provides a well-known source of inhibition in the brain, but the details on how this important inhibitory pathway affects neural circuits are lacking. We used sorting nexin 27 (SNX27), an endosom...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Rifkin, Robert A., Huyghe, Deborah, Li, Xiaofan, Parakala, Manasa, Aisenberg, Erin, Moss, Stephen J., Slesinger, Paul A.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6176583/
https://ncbi.nlm.nih.gov/pubmed/30228121
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1807788115
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