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SNX27 regulation of GIRK channels in VTA dopamine neurons attenuates in vivo cocaine response

The subcellular pathways that regulate G protein-gated inwardly rectifying potassium (GIRK or Kir3) channels are important for controlling the excitability of neurons. Sorting nexin 27 (SNX27) is a PDZ-containing protein known to bind GIRK2c/3 channels but its function in vivo is poorly understood....

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Munoz, Michaelanne B., Slesinger, Paul A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4141045/
https://ncbi.nlm.nih.gov/pubmed/24811384
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2014.03.011
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