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Contributions of the glycocalyx, endothelium, and extravascular compartment to the blood–brain barrier

The endothelial cells that form the blood–brain barrier (BBB) are coated with glycocalyx, on the luminal side, and with the basement membrane and astrocyte endfeet, on the abluminal side. However, it is unclear how exactly the glycocalyx and extravascular structures contribute to BBB properties. We...

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Publicado en:Proc Natl Acad Sci U S A
Main Authors: Kutuzov, Nikolay, Flyvbjerg, Henrik, Lauritzen, Martin
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2018
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6176561/
https://ncbi.nlm.nih.gov/pubmed/30217895
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1802155115
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