Endothelium-targeted overexpression of heat shock protein 27 ameliorates blood–brain barrier disruption after ischemic brain injury

The damage borne by the endothelial cells (ECs) forming the blood–brain barrier (BBB) during ischemic stroke and other neurological conditions disrupts the structure and function of the neurovascular unit and contributes to poor patient outcomes. We recently reported that structural aberrations in b...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Shi, Yejie, Jiang, Xiaoyan, Zhang, Lili, Pu, Hongjian, Hu, Xiaoming, Zhang, Wenting, Cai, Wei, Gao, Yanqin, Leak, Rehana K., Keep, Richard F., Bennett, Michael V. L., Chen, Jun
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2017
Assuntos:
PNAS Plus
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5320958/
https://ncbi.nlm.nih.gov/pubmed/28137866
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1621174114
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