A Qualitative Modeling Approach for Whole Genome Prediction Using High-Throughput Toxicogenomics Data and Pathway-Based Validation

Efficient high-throughput transcriptomics (HTT) tools promise inexpensive, rapid assessment of possible biological consequences of human and environmental exposures to tens of thousands of chemicals in commerce. HTT systems have used relatively small sets of gene expression measurements coupled with...

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Detalles Bibliográficos
Publicado en:Front Pharmacol
Main Authors: Haider, Saad, Black, Michael B., Parks, Bethany B., Foley, Briana, Wetmore, Barbara A., Andersen, Melvin E., Clewell, Rebecca A., Mansouri, Kamel, McMullen, Patrick D.
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2018
Assuntos:
Pharmacology
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6176017/
https://ncbi.nlm.nih.gov/pubmed/30333746
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2018.01072
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