Editor’s Highlight: Screening ToxCast Prioritized Chemicals for PPARG Function in a Human Adipose-Derived Stem Cell Model of Adipogenesis

The developmental origins of obesity hypothesis posits a multifaceted contribution of factors to the fetal origins of obesity and metabolic disease. Adipocyte hyperplasia in gestation and early childhood may result in predisposition for obesity later in life. Rodent in vitro and in vivo studies indi...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Toxicol Sci
Hauptverfasser: Foley, Briana, Doheny, Daniel L., Black, Michael B., Pendse, Salil N., Wetmore, Barbara A., Clewell, Rebecca A., Andersen, Melvin E., Deisenroth, Chad
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2017
Schlagworte:
PPAR-Gamma in ToxCast Chemicals
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5216650/
https://ncbi.nlm.nih.gov/pubmed/27664422
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfw186
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