Editor’s Highlight: Screening ToxCast Prioritized Chemicals for PPARG Function in a Human Adipose-Derived Stem Cell Model of Adipogenesis

The developmental origins of obesity hypothesis posits a multifaceted contribution of factors to the fetal origins of obesity and metabolic disease. Adipocyte hyperplasia in gestation and early childhood may result in predisposition for obesity later in life. Rodent in vitro and in vivo studies indi...

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Vydáno v:Toxicol Sci
Hlavní autoři: Foley, Briana, Doheny, Daniel L., Black, Michael B., Pendse, Salil N., Wetmore, Barbara A., Clewell, Rebecca A., Andersen, Melvin E., Deisenroth, Chad
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2017
Témata:
PPAR-Gamma in ToxCast Chemicals
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5216650/
https://ncbi.nlm.nih.gov/pubmed/27664422
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfw186
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