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Genetic Association of Pulmonary Surfactant Protein Genes, SFTPA1, SFTPA2, SFTPB, SFTPC, and SFTPD With Cystic Fibrosis

Surfactant proteins (SP) are involved in surfactant function and innate immunity in the human lung. Both lung function and innate immunity are altered in CF, and altered SP levels and genetic association are observed in Cystic Fibrosis (CF). We hypothesized that single nucleotide polymorphisms (SNPs...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Lin, Zhenwu, Thorenoor, Nithyananda, Wu, Rongling, DiAngelo, Susan L., Ye, Meixia, Thomas, Neal J., Liao, Xiaojie, Lin, Tony R., Warren, Stuart, Floros, Joanna
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6175982/
https://ncbi.nlm.nih.gov/pubmed/30333828
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.02256
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