Motifs within the CA-repeat-rich region of Surfactant Protein B (SFTPB) intron 4 differentially affect mRNA splicing

The first half of the surfactant protein B (SP-B) gene intron 4 is a CA-repeat-rich region that contains 11 motifs. To study the role of this region on SP-B mRNA splicing, minigenes were generated by systematic removal of motifs from either the 5′ or 3′ end. These were transfected in CHO cells to st...

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Главные авторы: Yang, Wenjun, Ni, Lan, Silveyra, Patricia, Wang, Guirong, Noutsios, Georgios T, Singh, Anamika, DiAngelo, Susan L, Sanusi, Olabisi, Raval, Manmeet, Floros, Joanna
Формат: Artigo
Язык:Inglês
Опубликовано: 2013
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3656664/
https://ncbi.nlm.nih.gov/pubmed/23687636
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