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The H3K9 methyltransferase SETDB1 maintains female identity in Drosophila germ cells
The preservation of germ cell sexual identity is essential for gametogenesis. Here we show that H3K9me3-mediated gene silencing is integral to female fate maintenance in Drosophila germ cells. Germ cell specific loss of the H3K9me3 pathway members, the H3K9 methyltransferase SETDB1, WDE, and HP1a, l...
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| Publicado no: | Nat Commun |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6175928/ https://ncbi.nlm.nih.gov/pubmed/30297796 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-06697-x |
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