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Matrix mechanical plasticity regulates cancer cell migration through confining microenvironments

Studies of cancer cell migration have found two modes: one that is protease-independent, requiring micron-sized pores or channels for cells to squeeze through, and one that is protease-dependent, relevant for confining nanoporous matrices such as basement membranes (BMs). However, many extracellular...

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Vydáno v:Nat Commun
Hlavní autoři: Wisdom, Katrina M., Adebowale, Kolade, Chang, Julie, Lee, Joanna Y., Nam, Sungmin, Desai, Rajiv, Rossen, Ninna Struck, Rafat, Marjan, West, Robert B., Hodgson, Louis, Chaudhuri, Ovijit
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6175826/
https://ncbi.nlm.nih.gov/pubmed/30297715
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-06641-z
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