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Interferon- Gamma- Inducible Guanosine Triphosphate Cyclohydrolase 1 (GTP-CH1) Pathway Is Associated with Frailty in Egyptian Elderly

BACKGROUND: Chronic low-grade inflammation may be a cardinal pathophysiologic feature in the pathogenesis of frailty. Interferon-gamma (INF-γ) is an understudied proinflammatory cytokine in frailty that induces many inflammatory pathways including the guanosine triphosphate cyclohydrolase 1 (GTP-CH1...

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Vydáno v:Rep Biochem Mol Biol
Hlavní autoři: Mohamad, Magda, Ebeid, Somaia, Shawky Khater, Mohamed, Alsadany, Mohamad
Médium: Artigo
Jazyk:Inglês
Vydáno: Varastegan Institute for Medical Sciences 2018
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6175590/
https://ncbi.nlm.nih.gov/pubmed/30324118
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