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Sequence Diversification by Divergent C-Terminal Elongation of Peptides

Sequence diversification at the C terminus is traditionally limited by significant epimerization of the C-terminal residue during its activation toward nucleophilic attack, thus mandating repetition of the peptide synthesis for each targeted variation. Here, we accomplish divergent C-terminal elonga...

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Detalhes bibliográficos
Publicado no:J Org Chem
Main Authors: Arbour, Christine A., Stamatin, Ramona E., Stockdill, Jennifer L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6175281/
https://ncbi.nlm.nih.gov/pubmed/29293336
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.joc.7b02655
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