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Point estimation following two‐stage adaptive threshold enrichment clinical trials
Recently, several study designs incorporating treatment effect assessment in biomarker‐based subpopulations have been proposed. Most statistical methodologies for such designs focus on the control of type I error rate and power. In this paper, we have developed point estimators for clinical trials t...
שמור ב:
| הוצא לאור ב: | Stat Med |
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| Main Authors: | , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
John Wiley and Sons Inc.
2018
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6175016/ https://ncbi.nlm.nih.gov/pubmed/29855066 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/sim.7831 |
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