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Point and interval estimation in two-stage adaptive designs with time to event data and biomarker-driven subpopulation selection
In personalized medicine, it is often desired to determine if all patients or only a subset of them benefit from a treatment. We consider estimation in two-stage adaptive designs that in stage 1 recruit patients from the full population. In stage 2, patient recruitment is restricted to the part of t...
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| Publicado no: | Stat Med |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7785132/ https://ncbi.nlm.nih.gov/pubmed/32363603 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/sim.8557 |
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