A Polyketide Synthase Component for Oxygen Insertion into Polyketide Backbones

Enzymatic core components from trans‐acyltransferase polyketide synthases (trans‐AT PKSs) catalyze exceptionally diverse biosynthetic transformations to generate structurally complex bioactive compounds. Here we focus on a group of oxygenases identified in various trans‐AT PKS pathways, including th...

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發表在:Angew Chem Int Ed Engl
Main Authors: Meoded, Roy A., Ueoka, Reiko, Helfrich, Eric J. N., Jensen, Katja, Magnus, Nancy, Piechulla, Birgit, Piel, Jörn
格式: Artigo
語言:Inglês
出版: John Wiley and Sons Inc. 2018
主題:
Communications
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6174933/
https://ncbi.nlm.nih.gov/pubmed/29898240
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201805363
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