Homocysteine causes vascular endothelial dysfunction by disrupting endoplasmic reticulum redox homeostasis

Endothelial dysfunction induced by hyperhomocysteinemia (HHcy) plays a critical role in vascular pathology. However, little is known about the role of endoplasmic reticulum (ER) redox homeostasis in HHcy-induced endothelial dysfunction. Here, we show that Hcy induces ER oxidoreductin-1α (Ero1α) expr...

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Detalles Bibliográficos
Publicado en:Redox Biol
Autores principales: Wu, Xun, Zhang, Lihui, Miao, Yütong, Yang, Juan, Wang, Xian, Wang, Chih-chen, Feng, Juan, Wang, Lei
Formato: Artigo
Lenguaje:Inglês
Publicado: Elsevier 2018
Materias:
Research Paper
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6174864/
https://ncbi.nlm.nih.gov/pubmed/30292945
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2018.09.021
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