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Origin of the Autophagosome Membrane in Mammals
Autophagy begins with the nucleation of phagophores, which then expand to give rise to the double-membrane autophagosomes. Autophagosomes ultimately fuse with lysosomes, where the cytosolic cargoes are degraded. Accumulation of autophagosomes is a hallmark of autophagy and neurodegenerative disorder...
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| Publié dans: | Biomed Res Int |
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| Auteurs principaux: | , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Hindawi
2018
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6174804/ https://ncbi.nlm.nih.gov/pubmed/30345294 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2018/1012789 |
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