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Origin of the Autophagosome Membrane in Mammals
Autophagy begins with the nucleation of phagophores, which then expand to give rise to the double-membrane autophagosomes. Autophagosomes ultimately fuse with lysosomes, where the cytosolic cargoes are degraded. Accumulation of autophagosomes is a hallmark of autophagy and neurodegenerative disorder...
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Publicado no: | Biomed Res Int |
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Main Authors: | , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Hindawi
2018
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6174804/ https://ncbi.nlm.nih.gov/pubmed/30345294 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2018/1012789 |
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