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Origin of the Autophagosome Membrane in Mammals
Autophagy begins with the nucleation of phagophores, which then expand to give rise to the double-membrane autophagosomes. Autophagosomes ultimately fuse with lysosomes, where the cytosolic cargoes are degraded. Accumulation of autophagosomes is a hallmark of autophagy and neurodegenerative disorder...
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主要な著者: | , , , , |
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フォーマット: | Artigo |
言語: | Inglês |
出版事項: |
Hindawi Limited
2018-01-01
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シリーズ: | BioMed Research International |
オンライン・アクセス: | http://dx.doi.org/10.1155/2018/1012789 |
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