Vaccination with chemically attenuated Plasmodium falciparum asexual blood-stage parasites induces parasite-specific cellular immune responses in malaria-naïve volunteers: a pilot study

BACKGROUND: The continuing morbidity and mortality associated with infection with malaria parasites highlights the urgent need for a vaccine. The efficacy of sub-unit vaccines tested in clinical trials in malaria-endemic areas has thus far been disappointing, sparking renewed interest in the whole p...

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Detalhes bibliográficos
Publicado no:BMC Med
Main Authors: Stanisic, Danielle I., Fink, James, Mayer, Johanna, Coghill, Sarah, Gore, Letitia, Liu, Xue Q., El-Deeb, Ibrahim, Rodriguez, Ingrid B., Powell, Jessica, Willemsen, Nicole M., De, Sai Lata, Ho, Mei-Fong, Hoffman, Stephen L., Gerrard, John, Good, Michael F.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6174572/
https://ncbi.nlm.nih.gov/pubmed/30293531
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12916-018-1173-9
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