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Activity of bromodomain protein inhibitors/binders against asexual-stage Plasmodium falciparum parasites

Bromodomain-containing proteins (BDPs) are involved in the regulation of eukaryotic gene expression. Compounds that bind and/or inhibit BDPs are of interest as tools to better understand epigenetic regulation, and as possible drug leads for different diseases, including malaria. In this study, we as...

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Detalhes bibliográficos
Publicado no:Int J Parasitol Drugs Drug Resist
Main Authors: Chua, Ming Jang, Robaa, Dina, Skinner-Adams, Tina S., Sippl, Wolfgang, Andrews, Katherine T.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6039313/
https://ncbi.nlm.nih.gov/pubmed/29631126
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijpddr.2018.03.001
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