Infectivity of Plasmodium falciparum in Malaria-Naive Individuals Is Related to Knob Expression and Cytoadherence of the Parasite

Plasmodium falciparum is the most virulent human malaria parasite because of its ability to cytoadhere in the microvasculature. Nonhuman primate studies demonstrated relationships among knob expression, cytoadherence, and infectivity. This has not been examined in humans. Cultured clinical-grade P....

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Gepubliceerd in:Infect Immun
Hoofdauteurs: Stanisic, Danielle I., Gerrard, John, Fink, James, Griffin, Paul M., Liu, Xue Q., Sundac, Lana, Sekuloski, Silvana, Rodriguez, Ingrid B., Pingnet, Jolien, Yang, Yuedong, Zhou, Yaoqi, Trenholme, Katharine R., Wang, Claire Y. T., Hackett, Hazel, Chan, Jo-Anne A., Langer, Christine, Hanssen, Eric, Hoffman, Stephen L., Beeson, James G., McCarthy, James S., Good, Michael F.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology 2016
Onderwerpen:
Fungal and Parasitic Infections
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4995910/
https://ncbi.nlm.nih.gov/pubmed/27382019
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00414-16
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