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Structural basis of the filamin A actin-binding domain interaction with F-actin
Actin-crosslinking proteins assemble actin filaments into higher-order structures essential for orchestrating cell shape, adhesion and motility. Missense mutations in the tandem calponin homology (CH) domains of their actin-binding domains (ABDs) underlie numerous genetic diseases, but a molecular u...
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| Publicado no: | Nat Struct Mol Biol |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6173970/ https://ncbi.nlm.nih.gov/pubmed/30224736 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41594-018-0128-3 |
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