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The E3 ubiquitin ligase specificity subunit ASB2α targets filamins for proteasomal degradation by interacting with the filamin actin-binding domain

Filamins are an important family of actin-binding and crosslinking proteins that mediate remodeling of the actin cytoskeleton and maintain extracellular matrix connections by anchoring transmembrane proteins to actin filaments and linking them to intracellular signaling cascades. We recently found t...

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Détails bibliographiques
Auteurs principaux: Razinia, Ziba, Baldassarre, Massimiliano, Bouaouina, Mohamed, Lamsoul, Isabelle, Lutz, Pierre G., Calderwood, David A.
Format: Artigo
Langue:Inglês
Publié: Company of Biologists 2011
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3138704/
https://ncbi.nlm.nih.gov/pubmed/21750192
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.084343
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