Lin28 Signaling Supports Mammalian PNS and CNS Axon Regeneration

RNA-binding proteins Lin28a/b regulate cellular growth and tissue regeneration. Here, we investigated the role of Lin28 in the control of axon regeneration in postmitotic neurons. We find that Lin28a/b are both necessary and sufficient for supporting axon regeneration in mature sensory neurons throu...

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Pubblicato in:Cell Rep
Autori principali: Wang, Xue-Wei, Li, Qiao, Liu, Chang-Mei, Hall, Philip A., Jiang, Jing-Jing, Katchis, Christopher D., Kang, Sehwa, Dong, Bryan C., Li, Shuxin, Zhou, Feng-Quan
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2018
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6173831/
https://ncbi.nlm.nih.gov/pubmed/30184489
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2018.07.105
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