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Splenectomy modulates early immuno-inflammatory responses to trauma-hemorrhage and protects mice against secondary sepsis
In polytrauma patients, the impact of splenectomy is equivocal, ranging from negative to protective. We investigated the impact of splenectomy on immune responses in the 1(st)-hit polytrauma alone and on survival in the post-traumatic sepsis (2(nd) hit). Female BALB/c mice underwent polytrauma (1(st...
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| 出版年: | Sci Rep |
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| 主要な著者: | , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Nature Publishing Group UK
2018
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6173732/ https://ncbi.nlm.nih.gov/pubmed/30291296 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-33232-1 |
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