Structural properties of a haemophore facilitate targeted elimination of the pathogen Porphyromonas gingivalis

Porphyromonas gingivalis is a keystone bacterial pathogen of chronic periodontitis. P. gingivalis is unable to synthesise the porphyrin macrocycle and relies on exogenous porphyrin, including haem or haem biosynthesis intermediates from host sources. We show that under the iron-limited conditions pr...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Gao, Jin-Long, Kwan, Ann H., Yammine, Anthony, Zhou, Xiaoyan, Trewhella, Jill, Hugrass, Barbara M., Collins, Daniel A. T., Horne, James, Ye, Ping, Harty, Derek, Nguyen, Ky-Anh, Gell, David A., Hunter, Neil
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6173696/
https://ncbi.nlm.nih.gov/pubmed/30291238
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-06470-0
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