Structural properties of a haemophore facilitate targeted elimination of the pathogen Porphyromonas gingivalis

Porphyromonas gingivalis is a keystone bacterial pathogen of chronic periodontitis. P. gingivalis is unable to synthesise the porphyrin macrocycle and relies on exogenous porphyrin, including haem or haem biosynthesis intermediates from host sources. We show that under the iron-limited conditions pr...

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Publicat a:Nat Commun
Autors principals: Gao, Jin-Long, Kwan, Ann H., Yammine, Anthony, Zhou, Xiaoyan, Trewhella, Jill, Hugrass, Barbara M., Collins, Daniel A. T., Horne, James, Ye, Ping, Harty, Derek, Nguyen, Ky-Anh, Gell, David A., Hunter, Neil
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2018
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6173696/
https://ncbi.nlm.nih.gov/pubmed/30291238
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-06470-0
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