Selective prebiotic conversion of pyrimidine and purine anhydronucleosides into Watson-Crick base-pairing arabino-furanosyl nucleosides in water

Prebiotic nucleotide synthesis is crucial to understanding the origins of life on Earth. There are numerous candidates for life’s first nucleic acid, however, currently no prebiotic method to selectively and concurrently synthesise the canonical Watson–Crick base-pairing pyrimidine (C, U) and purine...

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Publicat a:Nat Commun
Autors principals: Roberts, Samuel J., Szabla, Rafał, Todd, Zoe R., Stairs, Shaun, Bučar, Dejan-Krešimir, Šponer, Jiří, Sasselov, Dimitar D., Powner, Matthew W.
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2018
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6172253/
https://ncbi.nlm.nih.gov/pubmed/30287815
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-06374-z
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