Selective prebiotic conversion of pyrimidine and purine anhydronucleosides into Watson-Crick base-pairing arabino-furanosyl nucleosides in water

Prebiotic nucleotide synthesis is crucial to understanding the origins of life on Earth. There are numerous candidates for life’s first nucleic acid, however, currently no prebiotic method to selectively and concurrently synthesise the canonical Watson–Crick base-pairing pyrimidine (C, U) and purine...

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Publicado no:Nat Commun
Main Authors: Roberts, Samuel J., Szabla, Rafał, Todd, Zoe R., Stairs, Shaun, Bučar, Dejan-Krešimir, Šponer, Jiří, Sasselov, Dimitar D., Powner, Matthew W.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6172253/
https://ncbi.nlm.nih.gov/pubmed/30287815
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-06374-z
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