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Identification of KLF9 and BCL3 as transcription factors that enhance reprogramming of primordial germ cells

Primordial germ cells (PGCs) are precursors of eggs and sperm. Although PGCs are unipotent cells in vivo, they are reprogrammed into pluripotent stem cells (PSCs), also known as embryonic germ cells (EGCs), in the presence of leukemia inhibitory factor and basic fibroblast growth factor (bFGF) in vi...

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Bibliografski detalji
Izdano u:PLoS One
Glavni autori: Otsuka, Kei, Takehara, Asuka, Chiba, Natsuko, Matsui, Yasuhisa
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2018
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6171932/
https://ncbi.nlm.nih.gov/pubmed/30286177
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0205004
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