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Distinct requirements for energy metabolism in mouse primordial germ cells and their reprogramming to embryonic germ cells

Primordial germ cells (PGCs), undifferentiated embryonic germ cells, are the only cells that have the ability to become gametes and to reacquire totipotency upon fertilization. It is generally understood that the development of PGCs proceeds through the expression of germ cell-specific transcription...

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Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Hayashi, Yohei, Otsuka, Kei, Ebina, Masayuki, Igarashi, Kaori, Takehara, Asuka, Matsumoto, Mitsuyo, Kanai, Akio, Igarashi, Kazuhiko, Soga, Tomoyoshi, Matsui, Yasuhisa
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2017
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5547595/
https://ncbi.nlm.nih.gov/pubmed/28716939
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1620915114
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