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B cell responses to apoptotic cells in MFG-E8-/- mice

Defective clearance of apoptotic cells in MFG-E8 deficient mice results in lupus-like disease in the mixed B6x129, but not pure B6 background. The lack of overt autoimmunity in MFG-E8-/- B6 mice suggests that accumulation of apoptotic cells is not sufficient to break central tolerance. However, the...

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Bibliografske podrobnosti
izdano v:PLoS One
Glavni avtor: Peng, YuFeng
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2018
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6171925/
https://ncbi.nlm.nih.gov/pubmed/30286201
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0205172
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