Tumorigenicity-associated characteristics of human iPS cell lines

Human induced pluripotent stem cells (hiPSCs) represent promising raw materials of human cell-based therapeutic products (hCTPs). As undifferentiated hiPSCs exhibit intrinsic tumorigenicity properties that enable them to form teratomas, hCTPs containing residual undifferentiated hiPSCs may cause tum...

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Udgivet i:PLoS One
Main Authors: Yasuda, Satoshi, Kusakawa, Shinji, Kuroda, Takuya, Miura, Takumi, Tano, Keiko, Takada, Nozomi, Matsuyama, Satoko, Matsuyama, Akifumi, Nasu, Michiyo, Umezawa, Akihiro, Hayakawa, Takao, Tsutsumi, Hideki, Sato, Yoji
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2018
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6171902/
https://ncbi.nlm.nih.gov/pubmed/30286143
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0205022
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