SALL3 expression balance underlies lineage biases in human induced pluripotent stem cell differentiation

Clinical applications of human induced pluripotent stem cells (hiPSCs) are expected, but hiPSC lines vary in their differentiation propensity. For efficient selection of hiPSC lines suitable for differentiation into desired cell lineages, here we identify SALL3 as a marker to predict differentiation...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Nat Commun
Prif Awduron: Kuroda, Takuya, Yasuda, Satoshi, Tachi, Shiori, Matsuyama, Satoko, Kusakawa, Shinji, Tano, Keiko, Miura, Takumi, Matsuyama, Akifumi, Sato, Yoji
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group UK 2019
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6520385/
https://ncbi.nlm.nih.gov/pubmed/31092818
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-09511-4
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