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SALL3 expression balance underlies lineage biases in human induced pluripotent stem cell differentiation

Clinical applications of human induced pluripotent stem cells (hiPSCs) are expected, but hiPSC lines vary in their differentiation propensity. For efficient selection of hiPSC lines suitable for differentiation into desired cell lineages, here we identify SALL3 as a marker to predict differentiation...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Nat Commun
Hauptverfasser: Kuroda, Takuya, Yasuda, Satoshi, Tachi, Shiori, Matsuyama, Satoko, Kusakawa, Shinji, Tano, Keiko, Miura, Takumi, Matsuyama, Akifumi, Sato, Yoji
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6520385/
https://ncbi.nlm.nih.gov/pubmed/31092818
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-09511-4
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