1,25-Dihydroxyvitamin D suppresses M1 macrophages and promotes M2 differentiation at bone injury sites

An indispensable role of macrophages in bone repair has been well recognized. Previous data have demonstrated the copresence of M1 macrophages and mesenchymal stem cells (MSCs) during the proinflammatory stage of bone repair. However, the exact role of M1 macrophages in MSC function and bone repair...

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Detalhes bibliográficos
Publicado no:JCI Insight
Main Authors: Wasnik, Samiksha, Rundle, Charles H., Baylink, David J., Yazdi, Mohammad Safaie, Carreon, Edmundo E., Xu, Yi, Qin, Xuezhong, Lau, Kin-Hing William, Tang, Xiaolei
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6171806/
https://ncbi.nlm.nih.gov/pubmed/30185660
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.98773
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