Cyclooxygenase 2 augments osteoblastic but suppresses chondrocytic differentiation of CD90(+) skeletal stem cells in fracture sites

Cyclooxygenase 2 (COX-2) is essential for normal tissue repair. Although COX-2 is known to enhance the differentiation of mesenchymal stem cells (MSCs), how COX-2 regulates MSC differentiation into different tissue-specific progenitors to promote tissue repair remains unknown. Because it has been sh...

Full description

Saved in:
Bibliographic Details
Published in:Sci Adv
Main Authors: Wasnik, Samiksha, Lakhan, Ram, Baylink, David J., Rundle, Charles H., Xu, Yi, Zhang, Jintao, Qin, Xuezhong, Lau, Kin-Hing William, Carreon, Edmundo E., Tang, Xiaolei
Format: Artigo
Language:Inglês
Published: American Association for the Advancement of Science 2019
Subjects:
Research Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6669009/
https://ncbi.nlm.nih.gov/pubmed/31392271
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.aaw2108
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items