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The NOTCH4-HEY1 pathway induces epithelial mesenchymal transition in head and neck squamous cell carcinoma

BACKGROUND: Recently, several comprehensive genomic analyses demonstrated NOTCH1 and NOTCH3 mutations in head and neck squamous cell carcinoma (HNSCC) in approximately 20% of cases. Similar to other types of cancers, these studies also indicate that the NOTCH pathway is closely related to HNSCC prog...

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Detalhes bibliográficos
Publicado no:Clin Cancer Res
Main Authors: Fukusumi, Takahito, Guo, Theresa W, Sakai, Akihiro, Ando, Mizuo, Ren, Shuling, Haft, Sunny, Liu, Chao, Amornphimoltham, Panomwat, Gutkind, J. Silvio, Califano, Joseph A
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6171749/
https://ncbi.nlm.nih.gov/pubmed/29146722
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-17-1366
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